Stop, Reduce and Relieve with Daflon

An oral treatment for relieving leg pain, bulging veins on the legs and ankles, edema and other symptoms of chronic venous insufficiency. 2,5

Do Your Legs Feel Heavy, Swollen and Sore?

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You could be experiencing the first signs of Chronic Venous Insufficiency. Daflon helps reduce and relieve the following signs and symptoms associated with this progressive condition 2,5 :

feet of a heavy painful swollen leg

Edema or Feeling of Swelling

Heaviness Legs

Cramping or Leg pain

Spider Veins or Varicose Veins

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Do you suffer from anal pain, bleeding and itching?

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You could be experiencing the uncomfortable anal pain, itching and bleeding. Daflon acts quickly to reduce and relieve the following signs and symptoms of acute and recurring anal pain: 1,3

Incomplete evacuation

Bleeding

Itchy bottom

Anal pain or discomfort

Safety Information:

Daflon 500mg Safety Information

COMPOSITION*: Micronized, purified flavonoid fraction 500 mg: 450 mg diosmin; 50 mg flavonoids expressed as hesperidine. Micronized, purified flavonoid fraction 1000 mg: 900 mg diosmin; 100 mg flavonoids expressed as hesperidine. INDICATION*: This medicine is a venotonic (it increases venous tone) and a vasculoprotector (it increases resistance in small blood vessels). It is recommended for treating venous circulation disorders (heavy legs, pain, restless legs) and functional signs related to haemorrhoidal attack. DOSAGE AND ADMINISTRATION*: In venous disease: 1000mg daily. In acute hemorrhoidal attacks: the dosage can be increased up to 3000mg daily. CONTRAINDICATIONS*: Hypersensitivity to the active substance or to any of the excipients. WARNINGS*: The administration of this product for the symptomatic treatment of acute hemorrhoids does not preclude treatment for other anal conditions. If symptoms do not subside promptly, a proctological examination should be performed and the treatment should be reviewed. Excipients: 500mg and 1000mg tablet and 1000mg tablet orange aroma: sodium-free. 1000mg chewable tablet orange aroma: contains sorbitol and benzyl alcohol. 1000mg tablet orange aroma: contains benzyl alcohol. 1000mg oral suspension: patients with rare hereditary problems of fructose intolerance should not take this medicine. INTERACTION(S): None. FERTILITY. PREGNANCY/ LACTATION*: Treatment should be avoided. DRIVE & USE MACHINES*. UNDESIRABLE EFFECTS*: Common: diarrhoea, dyspepsia, nausea, vomiting. Rare: dizziness, headache, malaise, rash, pruritus, urticaria. Uncommon: colitis. Frequency not known: abdominal pain, isolated face, lip, eyelid oedema. Exceptionally Quincke's oedema. OVERDOSE*. PROPERTIES*: Vascular protector and venotonic. daflon® acts on the return vascular system: it reduces venous distensibility and venous stasis; in the microcirculation, it normalizes capillary permeability and reinforces capillary resistance. PRESENTATION*. SERVIER HONG KONG LIMITED, Flat 08-09, 43/F, Times Square Tower One, 1 Matheson Street, Causeway Bay, Hong Kong. www.servier.hk *For complete information, please refer to the Summary of Product Characteristics

Daflon 1000mg Safety Information

COMPOSITION*: Micronized, purified flavonoid fraction 500 mg: 450 mg diosmin; 50 mg flavonoids expressed as hesperidine. Micronized, purified flavonoid fraction 1000 mg: 900 mg diosmin; 100 mg flavonoids expressed as hesperidine. INDICATION*: This medicine is a venotonic (it increases venous tone) and a vasculoprotector (it increases resistance in small blood vessels). It is recommended for treating venous circulation disorders (heavy legs, pain, restless legs) and functional signs related to haemorrhoidal attack. DOSAGE AND ADMINISTRATION*: In venous disease: 1000mg daily. In acute hemorrhoidal attacks: the dosage can be increased up to 3000mg daily. CONTRAINDICATIONS*: Hypersensitivity to the active substance or to any of the excipients. WARNINGS*: The administration of this product for the symptomatic treatment of acute hemorrhoids does not preclude treatment for other anal conditions. If symptoms do not subside promptly, a proctological examination should be performed and the treatment should be reviewed. Excipients: 500mg and 1000mg tablet and 1000mg tablet orange aroma: sodium-free. 1000mg chewable tablet orange aroma: contains sorbitol and benzyl alcohol. 1000mg tablet orange aroma: contains benzyl alcohol. 1000mg oral suspension: patients with rare hereditary problems of fructose intolerance should not take this medicine. INTERACTION(S): None. FERTILITY. PREGNANCY/ LACTATION*: Treatment should be avoided. DRIVE & USE MACHINES*. UNDESIRABLE EFFECTS*: Common: diarrhoea, dyspepsia, nausea, vomiting. Rare: dizziness, headache, malaise, rash, pruritus, urticaria. Uncommon: colitis. Frequency not known: abdominal pain, isolated face, lip, eyelid oedema. Exceptionally Quincke's oedema. OVERDOSE*. PROPERTIES*: Vascular protector and venotonic. daflon® acts on the return vascular system: it reduces venous distensibility and venous stasis; in the microcirculation, it normalizes capillary permeability and reinforces capillary resistance. PRESENTATION*. SERVIER HONG KONG LIMITED, Flat 08-09, 43/F, Times Square Tower One, 1 Matheson Street, Causeway Bay, Hong Kong. www.servier.hk *For complete information, please refer to the Summary of Product Characteristics

References:

  1. Shelygin Y, et al. Curr Med Res Opin. 2016;32(11):1821-1826. DOI: 10.1080/03007995.2016.1211520.
  2. Nicolaides A, et al. Part I. Int Angiol. 2018;37(3):181-254.
  3. Godeberge P, et al. J Comp Eff Res 2021;10(10):801-813.
  4. Godeberge P, et al., J. Gastroenterol and Hepatol. 2020; 35:577-585. DOI:10.1111/jgh.14857.
  5. Nicolaides A, et al. International Angiology. 2020 Part II; DOI: 10.23736/S0392-9590.20.04388-6.

2025